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 AssociateProf. Yuting Li 
 Neural& Tumor Stem Cells 
 Instituteof WuYa 
 ShenyangPharmaceutical University 
 110016 Shenyang 
 Liaoning Province 
 
 Tel: +86 2423986282 
 E-Mail: <a href="mailto:liyuting200380@hotmail.com" style="font-family: 'Arial','sans-serif'; color: blue; font-size: 16px">liyuting200380@hotmail.com</a> 
 
 <h2 style="margin-bottom: 0px; background: rgb(167,167,167)">Selected Publications</h2> 
 ·    Yuting Li,Schmidt-Edelkraut U, Poetz F, Oliva I, Mandl C, Hölzl-Wenig G, Schönig K,Bartsch D, Ciccolini F. GABAAR Regulates AQP4 Expression in theSubependymal Zone: Relevance to Neural Precursors and Water Exchange. JBiol Chem. 2015, 290:4344-4355. (IF:4.573) 
 ·    Tiziana Cesetti, FrancescaCiccolini, and Yuting Li.GABA Not Only a Neurotransmitter: Osmotic Regulation by GABA(A)RSignaling. Front Cell Neurosci. 2012; 6: 3. (Review) (IF: 4.609) 
 ·    Yuting Li,Haohong Li, Xing Liu, Guobin Bao, Yezheng Tao, Ziyan Wu, Peng Xia, Chunfu Wu,Baoming Li, Lan Ma. Regulation of amygdalar PKA by β-arrestin 2/phosphodiesterase-4 complex is critical for fear conditioning. PNAS,2009, 106 (51): 21918-21923. (IF: 9.423) 
 ·    Yuting Li,Xing Liu, Chang Liu, Jiuhong Kang, Jingyu Yang, Gang Pei, Chunfu Wu.Improvement of morphine-mediated analgesia by inhibition of β-arrestin 2expression in mice periaqueductal gray matter. Int J Mol Sci. 2009,10(3): 954-963. (IF: 3.257) 
 ·    Guobinbao*, Lin Kang*, Haohong Li*, Yuting Li*,Lu Pu, Peng Xia, Lan Ma, Gang Pei. Morphine and heroindifferentially modulate in vivo hippocampal LTP in opiate dependent rat. Neuropsychopharmacology,2007, 32(8):1738-1749 (*,equal contribution) (IF: 6.399) 
 ·    Tiziana Cesetti, TatianaFila, Kirsten Obernier, C. Peter Bengtson, Yuting Li,Claudia Mandl, Gabriele Hölzl-Wenig, Francesca Ciccolini. GABAAReceptor Signaling Induces Osmotic Swelling and Cell Cycle Activation ofNeonatal Prominin+ Precursors. Stem Cells. 2011, 29 (2):307-319. (IF: 5.902) 
 ·    Haiping Deng, Zhijie Yang, Yuting Li, Guobin Bao, ThomasFriedrich, Quanbao Gu, Xueyong Shen, Wolfgang Schwarz. Interactions of Na+,K+-ATPase and co-expressed delta-opioid receptor. NeurosciRes. 2009, 65 (3): 222-227. (IF:2.004) 
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 <h1 style="margin-bottom: 15px">Group of Neural &Tumor Stem Cells </h1> 
 <h2 style="margin-bottom: 30px">Associate Prof. YutingLi</h2> 
 <h2 style="text-justify: inter-ideograph; text-align: justify">Neural stem cellsare essential for maintaining regenerative tissues and are critical componentsof repair in response to brain injury, infection and neurodegenerative diseases.Active adultneurogenesis is one of the most important discoveries inneuroscience within the last decades. There are two largest germinal zones for sustainingneurogenesis during adulthood in the mammalian central nervous system: the subventricular zone(SVZ) of the lateral ventricle (LV) and the subgranular zone (SGZ) of thedentate gyrus (DG) in the hippocampus.Strikingly, geneticalterations of stem cells and their progeny can lead to the generation of cancerstem cells that drive tumorigenesis in hierarchically organized cancerentities. </h2> 
 <h2 style="text-justify: inter-ideograph; text-align: justify">We mainly apply mouse models, in which geneticmutations are introduced specifically in neural and cancer stem cells. Our labaims:</h2> 
 <h2 style="text-justify: inter-ideograph; text-align: justify; margin-left: 51px">1)   To elucidate the crucial molecular and cellular basis of neural stem cells and cancerstem cells in the central nervous systemin vitroand in vivo. Weapply state-of-the-art genomic,genetic, molecular and cellular methods to reveal related mechanismsthatdrivenormal and uncontrolledself-renewal as well as therapy resistance.</h2> 
 <h2 style="text-justify: inter-ideograph; text-align: justify; margin-left: 51px">2)   Toestablish Chinese medicine network pharmacology responding specifically to neuralstem cells and cancer stem cells for therapeutical target screening ofneurodegenerative diseases and glioblastoma.</h2> 
 
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