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 个人信息： 
 性别：男  出生年月：1987/05  Email：<a href="mailto:to-qinbin@163.com" style="font-family: 'Times New Roman'; color: blue; text-decoration: underline">to-qinbin@163.com</a> 
 
 工作经历： 
 2016/04-今，特聘教授，沈阳药科大学 
 
 教育背景： 
 2013/10-2016/03，博士后，日本东京大学 
 2010/09-2013/07，博士，沈阳药科大学 
 2008/09-2010/07，硕士，沈阳药科大学 
 2004/09-2008/07，学士，沈阳药科大学 
 
 研究方向： 
 1. 生物催化：生物催化剂的发现及挖掘；通过蛋白质工程提高生物催化剂的活性及选择性；手性药物及其中间体的生物催化合成；活性天然产物的生物转化； 
 2. 生物合成：天然产物及其生物合成基因簇的挖掘；生物合成基因簇中关键酶的催化机制；萜合成酶及萜类化合物的生物合成； 
 3. 合成生物学：天然产物及非天然产物的生物合成； 
 
 代表性论文： 
 1. Bin Qin†, YudaiMatsuda†, Takahiro Mori, Masahiro Okada, Zhiyang Quan, Takaaki Mitsuhashi, ToshiyukiWakimoto, Ikuro Abe, An unusual chimeric diterpene synthase from Emericellavariecolor and its functional conversion to a sesterterpene synthase bydomain swapping. Angewandte Chemie International Edition 2016, 55(5), 1658-1661.(†Contributed equally)（封面文章，IF: 11.709） 
 2. Fengyu Qin†, Bin Qin†, Takahiro Mori, Yan Wang, Lingxin Meng, Xin Zhang,Xian Jia, Ikuro Abe, Song You, Engineering of Candida glabrata ketoreductase 1 for asymmetric reduction of α-haloketones. 
 ACS Catalysis2016, 6 (9), 6135-6140. (†Contributed equally) （IF: 9.307） 
 3. Masahiro Okada, Yudai Matsuda,Takaaki Mitsuhashi, Shotaro Hoshino, Takahiro Mori, Kazuya Nakagawa, ZhiyangQuan, Bin Qin, Huiping Zhang,Fumiaki Hayashi, Hiroshi Kawaide, Ikuro Abe,Genome-based discovery of anunprecedented cyclization mode in fungal sesterterpenoids biosynthesis.Journal of the American Chemical Society2016,138 (31), 10011-10018. （IF: 13.038） 
 4. Bin Qin, Yuxin Li,Lingxin Meng, Jingping Ouyang, Danni Jin, Lei Wu, Xin Zhang, Xian Jia, SongYou, “Mirror-Image” manipulation of curdione stereoisomer scaffolds by chemicaland biological approaches: development of a sesquiterpenoid library. Journalof Natural Products2015, 78 (2), 272-278.（IF: 3.662） 
 5. Bin Qin, Ping Liang,Xian Jia, Xin Zhang, Mao Mu, Xiaoying Wang, Guozhen Ma, Danni Jin, Song You,Directed evolution of Candida antarctica lipase B for kinetic resolutionof profen esters. Catalysis Communications 2013, 38, 1-5.（ IF: 3.389） 
 6. Ping Liang†, Bin Qin†,Mao Mu, Xin Zhang, Xian Jia, Song You, Prelog and anti-Prelog stereoselectivityof two ketoreductases from Candida glabrata. Biotechnology Letters 2013,35 (9), 1469-1473. (†Contributed equally)（ IF: 1.639） 
 
 Bin Qin 
 Associate Professor, Shenyang PharmaceuticalUniversity 
 Email: to-qinbin@163.com 
 
 ProfessionalExperience 
 2016/04-Current, Associate Professor, ShenyangPharmaceutical University, China 
 
 Education   
 2013/10-2016/03, Postdoctoral Fellow, TheUniversity of Tokyo, Japan 
 2010/09-2013/07, Ph.D., Shenyang PharmaceuticalUniversity, China 
 2008/09-2010/07, M.S., Shenyang PharmaceuticalUniversity, China 
 2004/09-2008/07, B.S., Shenyang PharmaceuticalUniversity, China 
 
 Research 
 1. Biocatalysis: Discovery and mining ofbiocatalysts; Protein engineering of biocatalysts to improve their activity andselectivity; Biocatalytic synthesis of pharmaceuticals and their keyintermediates; Biotransformation of active natural products; 
 2. Biosynthesis: Genome mining of natural productsand their biosynthetic gene clusters; Mechanism study of key enzymes in thebiosynthetic pathway; Terpene cyclases, biosynthesis and diversification ofterpenoids; 
 3. Synthetic biology:Synthetic biology of natural or non-natural products; 
 
 SelectedPublications 
 1. Bin Qin†, YudaiMatsuda†, Takahiro Mori, Masahiro Okada, Zhiyang Quan, Takaaki Mitsuhashi,Toshiyuki Wakimoto, Ikuro Abe, An unusual chimeric diterpene synthase from Emericellavariecolor and its functional conversion to a sesterterpene synthase bydomain swapping. Angewandte Chemie International Edition 2016, 55(5), 1658-1661.(†Contributed equally) 
 2. Fengyu Qin†, Bin Qin†, Takahiro Mori, Yan Wang, Lingxin Meng, Xin Zhang,Xian Jia, Ikuro Abe, Song You, Engineering of Candida glabrata ketoreductase 1 for asymmetric reduction of α-haloketones. 
 ACS Catalysis2016, 6 (9), 6135-6140. (†Contributed equally) 
 3. Masahiro Okada, Yudai Matsuda,Takaaki Mitsuhashi, Shotaro Hoshino, Takahiro Mori, Kazuya Nakagawa, ZhiyangQuan, Bin Qin, Huiping Zhang,Fumiaki Hayashi, Hiroshi Kawaide, Ikuro Abe,Genome-based discovery of anunprecedented cyclization mode in fungal sesterterpenoids biosynthesis.Journal of the American Chemical Society2016,138 (31), 10011-10018. 
 4. Bin Qin, Yuxin Li, LingxinMeng, Jingping Ouyang, Danni Jin, Lei Wu, Xin Zhang, Xian Jia, Song You,“Mirror-Image” manipulation of curdione stereoisomer scaffolds by chemical andbiological approaches: development of a sesquiterpenoid library. Journal ofNatural Products2015, 78 (2), 272-278. 
 5. Bin Qin, Ping Liang,Xian Jia, Xin Zhang, Mao Mu, Xiaoying Wang, Guozhen Ma, Danni Jin, Song You,Directed evolution of Candida antarctica lipase B for kinetic resolutionof profen esters. Catalysis Communications 2013, 38, 1-5. 
 6. Ping Liang†, Bin Qin†,Mao Mu, Xin Zhang, Xian Jia, Song You, Prelog and anti-Prelog stereoselectivityof two ketoreductases from Candida glabrata. Biotechnology Letters 2013,35 (9), 1469-1473. (†Contributed equally) 
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